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1

Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype

Metz, Stefan W., Thomas, Ashlie, Brackbill, Alex, Xianwen, Yi, Stone, Michele, Horvath, Katie, Miley, Michael J., Luft, Chris, DeSimone, Joseph M., Tian, Shaomin, de Silva, Aravinda M., Beasley, David

Journal:

PLoS Neglected Tropical Diseases

Year:

2018

Language:

english

File:

PDF, 3.07 MB

english, 2018

2

The Human Antibody Response to Dengue Virus Infection

Wahala, Wahala M. P. B., de Silva, Aravinda M.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

3

A Novel Universal Neutralizing Monoclonal Antibody against Enterovirus 71 That Targets the Highly Conserved “Knob” Region of VP3 Protein

Kiener, Tanja K., Jia, Qiang, Meng, Tao, Chow, Vincent Tak Kwong, Kwang, Jimmy, de Silva, Aravinda M.

Journal:

PLoS Neglected Tropical Diseases

Year:

2014

Language:

english

File:

PDF, 17.57 MB

english, 2014

4

Randomized, double-blind, comparative study on efficacy and safety of itraconazole pulse therapy and terbinafine pulse therapy on nondermatophyte mold onychomycosis: A study with 90 patients

Ranawaka, Ranthilaka R., Nagahawatte, Ajith, Gunasekara, Thusitha Aravinda, Weerakoon, Hema S., de Silva, S. H. Padmal

Journal:

Journal of Dermatological Treatment

Year:

2015

Language:

english

File:

PDF, 759 KB

english, 2015

5

Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses

Coffman, Jason E., Metz, Stefan W., Brackbill, Alex, Paul, Molly, Miley, Michael J., DeSimone, Joseph, Luft, J. Christopher, de Silva, Aravinda, Tian, Shaomin

Journal:

Bioconjugate Chemistry

Year:

2018

Language:

english

File:

PDF, 476 KB

english, 2018

6

Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody

W.M.P.B. Wahala, Annette A. Kraus, Laura B. Haymore, Mary Ann Accavitti-Loper, Aravinda M. de Silva

Journal:

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

7

Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes

Zhihua Kou, Joanne Y.H. Lim, Martina Beltramello, Matthew Quinn, Huiyuan Chen, Shengyo-ng Liu, Luis Martnez-Sobrido, Michael S. Diamond, Jacob J. Schlesinger, Aravinda de Silva, Federica Sallusto, Xia

Journal:

Year:

2011

Language:

english

File:

PDF, 818 KB

english, 2011

8

Corrigendum to “Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes” [Virology 410 (2011) 240–247]

Zhihua Kou, Joanne Y.H. Lim, Martina Beltramello, Matthew Quinn, Huiyuan Chen, Shengyong Liu, Luis Martinez-Sobrido, Michael S. Diamond, Jacob J. Schlesinger, Aravinda de Silva, Federica Sallusto, Xia

Journal:

Year:

2011

Language:

english

File:

PDF, 93 KB

english, 2011

9

Antibodies targeting dengue virus envelope domain III are not required for serotype-specific protection or prevention of enhancement in vivo

Katherine L. Williams, Wahala M.P.B. Wahala, Susana Orozco, Aravinda M. de Silva, Eva Harris

Journal:

Year:

2012

Language:

english

File:

PDF, 936 KB

english, 2012

10

Genetic analysis of Dengue 3 virus subtype III 5′ and 3′ non-coding regions

Ricardo L.A. Silva, Aravinda M. de Silva, Eva Harris, Gene H. MacDonald

Journal:

Year:

2008

Language:

english

File:

PDF, 898 KB

english, 2008

11

Arguments for live flavivirus vaccines

Aravinda de Silva, William Messer

Journal:

Year:

2004

Language:

english

File:

PDF, 36 KB

english, 2004

12

Evaluation of Venezuelan Equine Encephalitis (VEE) replicon-based Outer surface protein A (OspA) vaccines in a tick challenge mouse model of Lyme disease

Clay L. Gipson, Nancy L. Davis, Robert E. Johnston, Aravinda M. de Silva

Journal:

Year:

2003

Language:

english

File:

PDF, 298 KB

english, 2003

13

Glass Capillary Tube Feeding: A Method for Infecting Nymphal Ixodes scapularis (Acari: Ixodidae) with The Lyme Disease Spirochete Borrelia burgdorferi

Broadwater, Anne H., Sonenshine, Daniel E., Hynes, Wayne L., Ceraul, Shane, de Silva, Aravinda M.

Journal:

Journal of Medical Entomology

Year:

2002

Language:

english

File:

PDF, 257 KB

english, 2002

14

Dengue Virus Infection Mediated by DC-SIGN

Liu, Ping, Ridilla, Marc R., de Silva, Aravinda M., Thompson, Nancy L., Jacobson, Ken

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 49 KB

english, 2014

15

The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1

Zhou, Yang, Austin, S.Kyle, Fremont, Daved H., Yount, Boyd L., Huynh, Jeremy P., de Silva, Aravinda M., Baric, Ralph S., Messer, William B.

Journal:

Year:

2013

Language:

english

File:

PDF, 849 KB

english, 2013

16

Quality Control in the Endoplasmic Reticulum: Folding and Misfolding of Vesicular Stomatitis Virus G Protein in Cells and in vitro

Aravinda M. de Silva, William E. Balch and Ari Helenius

Journal:

The Journal of Cell Biology

Year:

1990

Language:

english

File:

PDF, 1.97 MB

english, 1990

17

Low Copy Numbers of DC-SIGN in Cell Membrane Microdomains: Implications for Structure and Function

Liu, Ping, Wang, Xiang, Itano, Michelle S., Neumann, Aaron K., de Silva, Aravinda M., Jacobson, Ken, Thompson, Nancy L.

Journal:

Year:

2014

Language:

english

File:

PDF, 18.09 MB

english, 2014

18

A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface

Fibriansah, Guntur, Tan, Joanne L, Smith, Scott A, de Alwis, Adamberage R, Ng, Thiam-Seng, Kostyuchenko, Victor A, Ibarra, Kristie D, Wang, Jiaqi, Harris, Eva, de Silva, Aravinda, Crowe, James E, Lok,

Journal:

EMBO Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 3.88 MB

english, 2014

19

Plasmid Requirements for Infection of Ticks by Borrelia burgdorferi

Strother, Keith O., Broadwater, Anne, De Silva, Aravinda

Journal:

Vector-Borne and Zoonotic Diseases

Year:

2005

Language:

english

File:

PDF, 84 KB

english, 2005

20

Immune Evasion by Tickborne and Host-Adapted Borrelia burgdorferi

Aravinda M. de Silva, Erol Fikrig, Emir Hodzic, Fred S. Kantor, Sam R. Telford III and Stephen W. Barthold

Journal:

The Journal of Infectious Diseases

Year:

1998

Language:

english

File:

PDF, 1.19 MB

english, 1998

21

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

Fibriansah, Guntur, Tan, Joanne L., Smith, Scott A., de Alwis, Ruklanthi, Ng, Thiam-Seng, Kostyuchenko, Victor A., Jadi, Ramesh S., Kukkaro, Petra, de Silva, Aravinda M., Crowe, James E., Lok, Shee-Me

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.38 MB

english, 2015

22

Immune Evasion by Tickborne and Host‐Adapted Borrelia burgdorferi

de Silva, Aravinda M., Fikrig, Erol, Hodzic, Emir, Kantor, Fred S., Telford III, Sam R., Barthold, Stephen W.

Journal:

The Journal of Infectious Diseases

Year:

1998

Language:

english

File:

PDF, 124 KB

english, 1998

23

FELIX PRASHANTHA AMERASINGHE 1948–2005

Konradsen, Flemming, de Silva, Aravinda, van der Hoek, Wim

Journal:

Journal of the American Mosquito Control Association

Year:

2005

Language:

english

File:

PDF, 16 KB

english, 2005

24

Development and Characterization of a Reverse Genetic System for Studying Dengue Virus Serotype 3 Strain Variation and Neutralization

Messer, William B., Yount, Boyd, Hacker, Kari E., Donaldson, Eric F., Huynh, Jeremy P., de Silva, Aravinda M., Baric, Ralph S., Rothman, Alan L.

Journal:

PLoS Neglected Tropical Diseases

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

25

Detection of Serotype-Specific Antibodies to the Four Dengue Viruses Using an Immune Complex Binding (ICB) ELISA

Emmerich, Petra, Mika, Angela, Schmitz, Herbert, de Silva, Aravinda M.

Journal:

PLoS Neglected Tropical Diseases

Year:

2013

Language:

english

File:

PDF, 898 KB

english, 2013

26

Natural Strain Variation and Antibody Neutralization of Dengue Serotype 3 Viruses

Wahala, Wahala M. P. B., Donaldson, Eric F., de Alwis, Ruklanthi, Accavitti-Loper, Mary Ann, Baric, Ralph S., de Silva, Aravinda M., Früh, Klaus

Journal:

Year:

2010

Language:

english

File:

PDF, 868 KB

english, 2010

27

Dengue Viruses Are Enhanced by Distinct Populations of Serotype Cross-Reactive Antibodies in Human Immune Sera

de Alwis, Ruklanthi, Williams, Katherine L., Schmid, Michael A., Lai, Chih-Yun, Patel, Bhumi, Smith, Scott A., Crowe, James E., Wang, Wei-Kung, Harris, Eva, de Silva, Aravinda M., Gack, Michaela U.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

28

Development of a Humanized Antibody with High Therapeutic Potential against Dengue Virus Type 2

Li, Pi-Chun, Liao, Mei-Ying, Cheng, Ping-Chang, Liang, Jian-Jong, Liu, I-Ju, Chiu, Chien-Yu, Lin, Yi-Ling, Chang, Gwong-Jen J., Wu, Han-Chung, de Silva, Aravinda M.

Journal:

PLoS Neglected Tropical Diseases

Year:

2012

Language:

english

File:

PDF, 2.31 MB

english, 2012

29

Estimates of Dengue Force of Infection in Children in Colombo, Sri Lanka

Tam, Clarence C., Tissera, Hasitha, de Silva, Aravinda M., De Silva, Aruna Dharshan, Margolis, Harold S., Amarasinge, Ananda, Morrison, Amy C.

Journal:

PLoS Neglected Tropical Diseases

Year:

2013

Language:

english

File:

PDF, 441 KB

english, 2013

30

International External Quality Assessment of Molecular Detection of Rift Valley Fever Virus

Escadafal, Camille, Paweska, Janusz T., Grobbelaar, Antoinette, le Roux, Chantel, Bouloy, Michèle, Patel, Pranav, Teichmann, Anette, Donoso-Mantke, Oliver, Niedrig, Matthias, de Silva, Aravinda M.

Journal:

PLoS Neglected Tropical Diseases

Year:

2013

Language:

english

File:

PDF, 176 KB

english, 2013

31

Differences in Type I Interferon Signaling Antagonism by Dengue Viruses in Human and Non-Human Primate Cell Lines

Medina, Freddy A., Torres-Malavé, Giselle, Chase, Amanda J., Santiago, Gilberto A., Medina, Juan F., Santiago, Luis M., Muñoz-Jordán, Jorge L., de Silva, Aravinda M

Journal:

PLoS Neglected Tropical Diseases

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

32

Synergistic Interactions between the NS3hel and E Proteins Contribute to the Virulence of Dengue Virus Type 1

de Borba, Luana, Strottmann, Daisy M., de Noronha, Lucia, Mason, Peter W., Duarte dos Santos, Claudia N., de Silva, Aravinda M.

Journal:

PLoS Neglected Tropical Diseases

Year:

2012

Language:

english

File:

PDF, 2.17 MB

english, 2012

33

Antibody-Dependent Enhancement Infection Facilitates Dengue Virus-Regulated Signaling of IL-10 Production in Monocytes

Tsai, Tsung-Ting, Chuang, Yi-Jui, Lin, Yee-Shin, Chang, Chih-Peng, Wan, Shu-Wen, Lin, Sheng-Hsiang, Chen, Chia-Ling, Lin, Chiou-Feng, de Silva, Aravinda M.

Journal:

PLoS Neglected Tropical Diseases

Year:

2014

Language:

english

File:

PDF, 1.93 MB

english, 2014

34

Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection

Callaway, Justin B., Smith, Scott A., McKinnon, Karen P., de Silva, Aravinda M., Crowe, James E., Ting, Jenny P.-Y.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 8.59 MB

english, 2015

35

Dengue virus infection elicits highly polarized CX3CR1 + cytotoxic CD4 + T cells associated with protective immunity

Weiskopf, Daniela, Bangs, Derek J., Sidney, John, Kolla, Ravi V., De Silva, Aruna D., de Silva, Aravinda M., Crotty, Shane, Peters, Bjoern, Sette, Alessandro

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.60 MB

english, 2015

36

Severe Dengue Epidemics in Sri Lanka, 2003–2006

Kanakaratne, Nalaka, Wahala, Wahala M.P.B., Messer, William B., Tissera, Hasitha A., Shahani, Aruna, Abeysinghe, Nihal, de Silva, Aravinda M., Gunasekera, Maya

Journal:

Emerging Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 494 KB

english, 2009

37

Contrasts in Tick Innate Immune Responses to Borrelia burgdorferi Challenge: Immunotolerance in Ixodes scapularis Versus Immunocompetence in Dermacentor variabilis (Acari: Ixodidae)

Johns, Robert, Ohnishi, Jun, Broadwater, Anne, Sonenshine, Daniel E., De Silva, Aravinda M., Hynes, Wayne L.

Journal:

Journal of Medical Entomology

Year:

2001

Language:

english

File:

PDF, 4.24 MB

english, 2001

38

Lack of Detectable Variation at Borrelia burgdorferi vlsE Locus in Ticks

Nosbisch, Leanna K., De Silva, Aravinda M.

Journal:

Journal of Medical Entomology

Year:

2007

Language:

english

File:

PDF, 278 KB

english, 2007

39

Characterization of Borrelia burgdorferi Aggregates

Srivastava, Siddharth Y., de Silva, Aravinda M.

Journal:

Vector-Borne and Zoonotic Diseases

Year:

2009

Language:

english

File:

PDF, 272 KB

english, 2009

40

Posttranslational Folding of Vesicular Stomatitis Virus G Protein in the ER: Involvement of Noncovalent and Covalent Complexes

Aravinda de Silva, Ineke Braakman and Ari Helenius

Journal:

The Journal of Cell Biology

Year:

1993

Language:

english

File:

PDF, 851 KB

english, 1993

41

The Emerging Zika Virus Epidemic in the Americas

Lazear, Helen M., Stringer, Elizabeth M., de Silva, Aravinda M.

Journal:

JAMA The Journal of the American Medical Association

Year:

2016

Language:

english

File:

PDF, 56 KB

english, 2016

42

Lack of Detectable Variation at Borrelia burgdorferi vlsE Locus in Ticks

Nosbisch, Leanna K., De Silva, Aravinda M.

Journal:

Journal of Medical Entomology

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

43

DC-SIGN Mediated Dengue Virus Entry into Cells

Jacobson, Kenneth, Liu, Ping, Ridilla, Marc, Betts, Laurie, de Silva, Aravinda, Thompson, Nancy L.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

44

Ticks Take Cues from Mammalian Interferon

de Silva, Aravinda M.

Journal:

Cell Host & Microbe

Year:

2016

Language:

english

File:

PDF, 192 KB

english, 2016

45

Dissecting antibodies induced by a chimeric yellow fever-dengue, live-attenuated, tetravalent dengue vaccine (CYD-TDV) in naïve and dengue exposed individuals

Henein, Sandra, Swanstrom, Jesica, Byers, Anthony M., Moser, Janice M., Shaik, S. Farzana, Bonaparte, Matthew, Jackson, Nicholas, Guy, Bruno, Baric, Ralph, de Silva, Aravinda M.

Journal:

The Journal of Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 2.32 MB

english, 2016

46

Epidemiology of dengue in Sri lanka before and after the emergence of epidemic dengue hemorrhagic fever

Messer, William B., Vitarana, U. Tissa, Sivananthan, Kamalanayani, Elvtigala, Jayanthi, Preethimala, L. D., Ramesh, R., Withana, Nalini, Gubler, Duane J., {De Silva}, Aravinda M.

Journal:

American Journal of Tropical Medicine and Hygiene

Year:

2002

Language:

english

File:

PDF, 107 KB

english, 2002

47

Novel and reported pathogenic variants in exon 11 ofBRCA2gene in a cohort of Sri Lankan young breast cancer patients

De Silva, Sumadee, Tennekoon, Kamani Hemamala, Dissanayake, Aravinda, De Silva, Kanishka, Jayasekara, Lakshika

Journal:

Familial Cancer

Year:

2017

Language:

english

File:

PDF, 602 KB

english, 2017

48

Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone

Gallichotte, Emily N., Menachery, Vineet D., Yount, Boyd L., Widman, Douglas G., Dinnon, Kenneth H., Hartman, Steven, de Silva, Aravinda M., Baric, Ralph S., Dutch, Rebecca Ellis

Journal:

Year:

2017

Language:

english

File:

PDF, 2.18 MB

english, 2017

49

Host response: Cross-fit T cells battle Zika virus

Collins, Matthew, de Silva, Aravinda

Journal:

Nature Microbiology

Year:

2017

Language:

english

File:

PDF, 378 KB

english, 2017

50

In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers

Metz, Stefan W., Gallichotte, Emily N., Brackbill, Alex, Premkumar, Lakshmanane, Miley, Michael J., Baric, Ralph, de Silva, Aravinda M.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.91 MB

english, 2017

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